Case 1 - Question 4 Choose an answer and hit "Submit." 4. Which of the following investigations is diagnostic for pemphigoid gestationis? A. Elevated serum levels of IgE B. No test is necessary; diagnosis of pemphigoid gestationis is purely clinical C. Skin biopsy from the perilesional area showing deposition of C3 along basement membrane on direct immunofluorescence D. Elevated serum total bile acid concentration Time's up